Research

Taking part in Research

The Manor Group is involved in medical research and from time to time you may be approached to take part. Taking part in research is voluntary: you can freely accept or decline, and this will not affect the care that you receive in any way. Even if you agree to take part, you can still withdraw at any time, without having to provide justification. Withdrawing from a study will NOT affect the care we provide for you.

All research projects carried out at the Manor Group have been thoroughly checked and approved by the relevant health authorities & ethical committees ensuring it is appropriate and safe to perform. You will always receive clear information about what taking part in a research study would involve and will have the opportunity to ask questions and obtain further details about a study. All projects are fully compliant with all UK laws (incl. GDPR).

• You may receive a text message, email or a letter in the post offering you the opportunity to take part in a study (the letter will include some information about the project).
• Your doctor or nurse may also discuss research opportunities during your usual appointment.
• You may also be approached by a member of the study team in the waiting area; be assured that this person and their activity will have been approved by the practice.

What you will be asked to do as part of the research will vary from study to study. The Patient Information Sheet for each project will detail what is expected of you. The study team is also there to answer all questions you may have

Is research right for me & what do patients taking part in research really think?

Ultimately, our research helps people to access and take part in studies which could potentially make a real difference to their health conditions and quality of life. Click on the links below to hear more from patients who have taken part in research: Click on the links to find out more information:

• Health talk: Patient and public involvement in research
• Clinical Research Network - Patient Research Experience Survey

What are the benefits of your practice being active in research?

Evidence suggests that patients who receive care in research-active institutions have better health outcomes than those who are treated in a non-research environment. By joining the research community, we are actively helping to improve the standard of healthcare for our patients.

Research provides an opportunity for you, the patient, to better understand your health conditions as well as give something back to the NHS and wider community. Sometimes it can provide patients with access to new treatments, as well as bringing a new dimension to practice and added skills to those involved.

The practice will receive funding to cover any additional costs of taking part in research (it does not come out of our own budget and so routine patient services will not be affected).

Things you may want to know

• Participation in research is entirely voluntary and you have the right to say ‘No’.  Nobody will put pressure on you to take part in research if you do not wish to.  You do not have to give us a reason if you decide not to take part.
• Your care and your relationship with your doctor or nurse will not be affected in any way if you decide not to take part in a research study.
• You will always receive clear information about what taking part in a research study would involve.  The practice will usually provide you with a patient information sheet; then, if you agree to take part, the study team will explain the study to you in more detail and you will have the opportunity to ask questions about it.
• Nobody from outside this practice will be given your contact details or have access to your medical records without your prior consent.  If you do agree to take part in a study, you will be asked to sign a consent form – this will clearly state which parts of your notes (if any) may be looked at for the purposes of the research.
• You will not be asked to take part in a large number of studies.  Most researchers are very specific about the criteria that people need to meet in order to enter their study.  Usually this means that only a relatively small number of patients at the practice will be suitable for any one study.

Your data for research (GDPR guidelines and Anonymous data)

If you do agree to take part in a study, you will be asked to sign a consent form. This will clearly state which parts of your medical notes (if any) may be looked at for the purposes of the research study. Nobody from outside your practice organisation will be given your contact details or have access to your medical records without your prior consent.

This practice is also participating in (x) national database project(s) which collects anonymised electronic medical records from GP surgeries throughout the UK.  Through the electronic clinical system we use to record medical notes, a completely anonymous (i.e. no identifiable patient details are shared at all) extract is taken which is used for medical research.  This clinical data is then catalogued and provides continuous monitoring of infection and disease around the UK.

Use of third-party document outsource processors (mailing companies)

Researchers regularly use document outsource processors such as Docmail to send study information to people who might be interested in taking part in clinical research. Only companies that are confirmed as being fully compliant with the laws surrounding data protection and data sharing, such as GDPR, are used. In addition to this, providers will be reviewed and permitted by the regulatory bodies that ethically approve, govern, and oversee clinical research taking place in the UK, such as the NHS Health Research Authority and Research Ethics Committees.

We would like to reassure you that, should you receive an invite to participate in a research study:

• The letter will have come directly from the practice. We do not share identifiable information with researchers without patient consent.
• It is our practice staff who perform research mailouts using the document outsource processor. Your contact details will not be shared outside of the system and will be deleted after 28 days.

What if I don’t want to get involved in research?

We recognise that some people may not want to receive information about research studies by post or text message. If you do not want to be contacted about research studies that we may run at the practice in the future, please let us know. If you change your mind at a later date, you can still opt back in at any time

To opt out of participating in any research studies visit the NHS Your Data Matters website to set your preferences

Our studies

Current and upcoming research:

• MONET - mechanisms and efficiency of neurodynamic exercises for mild to moderate carpal tunnel syndrome.
• DISCOVER ME - a nationwide research study looking at how health and genetic information can allow us to better understand disease, including ancestry testing and health results provided via a secure portal.
• COMPASS – efficacy of synthetic psychedelics with psychological support for reducing symptoms in treatment resistant depression.

Completed studies

• ANTLER - Antidpressants to prevent relapse in depression.
• DECIDE - ​To Determine the effectiveness of the treatment dapagliflozin compared to usual care for second line treatments.
• EMPA - A study testing whether a medicine called empagliflozin lowers the risk of worsening kidney or heart disease in patients with existing kidney disease.  This is a study being run by Oxford University at the Clinical Trials Unit at the Churchill Hospital.
• i-WOTCH - Improving the Wellbeing of People with Opioid Treated Chronic Pain.
• OPTIMISE-HF - Optimising managment of patients with Heart Failure with preserved ejection fraction​​.
• PREVAIL - Self Regulation intervention for weight loss.
• PRINCIPLE - Platform Randomised trial of Interventions against COVID-19 In older people. This trial is looking at a range of potential treatments for people over the age of 50 who develop any new COVID-19 symptoms.  Please click the link above if you would like to participate.
• STOIC - STerOids In Covid. Oxford University trial to assess whether a steroid inhaler is an effective treatment for COVID-19 infection.